Annotated Bibliography
Anders, Carolin, Ole Niewoehner, Alessia Duerst, and Martin Jinek. “Europe PMC Funders Group Structural Basis of PAM-Dependent Target DNA Recognition by the Cas9 Endonuclease.” Nature 513, no. 7519 (2015): 569–73. https://doi.org/10.1038/nature13579.Structural.
Arnold, Lesley M., Paul E. Keck, Jacqueline Collins, Rodgers Wilson, David E. Fleck, Kimberly B. Corey, Jennifer Amicone, Victor R. Adebimpe, and Stephen M. Strakowski. “Ethnicity and First-Rank Symptoms in Patients with Psychosis.” Schizophrenia Research 67, no. 2–3 (2004): 207–12. https://doi.org/10.1016/S0920-9964(02)00497-8.
Barrangou, Rodolphe, Cristophe Fremaux, Helene Deveau, Melissa Richards, Patrick Boyaval, Sylvain Moineau, Dennis A Romero, and Philippe Horvath. “CRISPR Provides Acquired Resistance Against Virses in Prokaryotes.” Science 315, no. March (2007): 1709–12. https://doi.org/10.1126/science.1138140.
Barrangou, Rodolphe, and Philippe Horvath. “A Decade of Discovery: CRISPR Functions and Applications.” Nature Microbiology 2, no. 7 (June 5, 2017): 17092. https://doi.org/10.1038/nmicrobiol.2017.92 This article summarizes the history behind CRISPR functions and its potential applications.
“Black Lightning (2018) Episode Scripts | SS.” Accessed August 16, 2018. https://www.springfieldspringfield.co.uk/episode_scripts.php?tv-show=black-lightning-2018 This website hosts scripts for many television shows and movies.
Bruist, Michael F. “A Simple Demonstration of How Intermolecular Forces Make DNA Helical.” Journal of Chemical Education 75, no. 1 (January 1998): 53. https://doi.org/10.1021/ed075p53 This is actually a classroom demonstration that I referenced for explaing the intermolecular forces present in DNA.
Charlesworth, Carsten Trevor, Priyanka S Deshpande, Daniel P Dever, Beruh Dejene, Natalia Gomez-Ospina, Sruthi Mantri, Mara Pavel-Dinu, Joab Camarena, Kenneth I Weinberg, and Matthew H Porteus. “Identification of Pre-Existing Adaptive Immunity to Cas9 Proteins in Humans.” BioRxiv, January 5, 2018, 243345. https://doi.org/10.1101/243345 This article has evidence supporting that the human immune system may possible reject the CRISPR technology.
Cunliffe, Vincent T. “The Epigenetic Impacts of Social Stress: How Does Social Adversity Become Biologically Embedded?” Epigenomics 8, no. 12 (December 21, 2016): 1653–69. https://doi.org/10.2217/epi-2016-0075.
Deverman, Benjamin E., Piers L. Pravdo, Bryan P. Simpson, Sripriya Ravindra Kumar, Ken Y. Chan, Abhik Banerjee, Wei Li Wu, et al. “Cre-Dependent Selection Yields AAV Variants for Widespread Gene Transfer to the Adult Brain.” Nature Biotechnology 34, no. 2 (February 1, 2016): 204–9. https://doi.org/10.1038/nbt.3440 This article is about a man-made virus engineered for safely delivering genetic material to brain cells.
Gara, M A, W A Vega, S Arndt, M Escamilla, D E Fleck, W B Lawson, I Lesser, et al. “Influence of Patient Race and Ethnicity on Clinical Assessment in Patients with Affective Disorders.” Archives of General Psychiatry 69, no. 6 (2012): 593–600. https://doi.org/10.1001/archgenpsychiatry.2011.2040.
Hamers, Laurel. “Cancer Cells Engineered with CRISPR Slay Their Own Kin.” Science News, 2018. https://www.sciencenews.org/article/cancer-cells-engineered-crispr-slay-their-own-kin.
Ho, Tsui-Ting, Nanjiang Zhou, Jianguo Huang, Pratirodh Koirala, Min Xu, Roland Fung, Fangting Wu, and Yin-Yuan Mo. “Targeting Non-Coding RNAs with the CRISPR/Cas9 System in Human Cell Lines.” Nucleic Acids Research 43, no. 3 (February 18, 2015): e17–e17. https://doi.org/10.1093/nar/gku1198.
Jones, Lauren J., and William H.J. Norton. “Using Zebrafish to Uncover the Genetic and Neural Basis of Aggression, a Frequent Comorbid Symptom of Psychiatric Disorders.” Behavioural Brain Research 276 (January 1, 2015): 171–80. https://doi.org/10.1016/J.BBR.2014.05.055.
Kalueff, AV, AM Stewart, R Gerlai - Trends in pharmacological sciences, and undefined 2014. “Zebrafish as an Emerging Model for Studying Complex Brain Disorders.” Elsevier. Accessed July 18, 2018. https://www.sciencedirect.com/science/article/pii/S0165614713002290.
Kirkbride, James B., Antonia Errazuriz, Tim J. Croudace, Craig Morgan, Daniel Jackson, Jane Boydell, Robin M. Murray, and Peter B. Jones. “Incidence of Schizophrenia and Other Psychoses in England, 1950–2009: A Systematic Review and Meta-Analyses.” Edited by James G. Scott. PLoS ONE 7, no. 3 (March 22, 2012): e31660. https://doi.org/10.1371/journal.pone.0031660.
Kleinstiver, Benjamin P., Michelle S. Prew, Shengdar Q. Tsai, Ved V. Topkar, Nhu T. Nguyen, Zongli Zheng, Andrew P.W. Gonzales, et al. “Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificities.” Nature 523, no. 7561 (2015): 481–85. https://doi.org/10.1038/nature14592.
Kowalski, Kathiann. “Can DNA Editing Save Endangered Species?” Science News for Students, 2018. https://www.sciencenewsforstudents.org/article/can-dna-editing-save-endangered-species.
Liu, Xiqiang, Cheng Wang, Zujian Chen, Yi Jin, Yun Wang, Antonia Kolokythas, Yang Dai, and Xiaofeng Zhou. “MicroRNA-138 Suppresses Epithelial-Mesenchymal Transition in Squamous Cell Carcinoma Cell Lines.” The Biochemical Journal 440, no. 1 (November 15, 2011): 23–31. https://doi.org/10.1042/BJ20111006.
Monosson, Emily. “Epigenetics: Epilogue or Prologue?” In Unnatural Selection, 143–53. Washington, DC: Island Press/Center for Resource Economics, 2015. https://doi.org/10.5822/978-1-61091-500-7_9 This book provided some insight into how genes are influenced by the environment that an organism lives in. This was a primary reading assignment in the seminar.
Nelson, Christopher E, Christopher E Nelson, Chady H Hakim, David G Ousterout, Pratiksha I Thakore, Eirik A Moreb, Ruth M Castellanos Rivera, et al. “In Vivo Genome Editing Improves Muscle Function in a Mouse Model of Duchenne Muscular Dystrophy.” Science 5143, no. December (2015): 1–8. https://doi.org/10.1126/science.aad5143.
Noble, Charleston, Ben Adlam, George M. Church, Kevin M. Esvelt, and Martin A. Nowak. “Current CRISPR Gene Drive Systems Are Likely to Be Highly Invasive in Wild Populations.” BioRxiv, 2017, 219022. https://doi.org/10.1101/219022.
Pan, Jin, Kai Li, Wei Huang, and Xiaoqing Zhang. “MiR-137 Inhibited Cell Proliferation and Migration of Vascular Smooth Muscle Cells via Targeting IGFBP-5 and Modulating the MTOR/STAT3 Signaling.” Edited by Gianfranco Pintus. PLOS ONE 12, no. 10 (October 10, 2017): e0186245. https://doi.org/10.1371/journal.pone.0186245.
Perlman, Greg, Roman Kotov, Jinmiao Fu, Evelyn J. Bromet, Laura J. Fochtmann, Helena Medeiros, Michele T. Pato, Carlos N. Pato, and Carlos N. Pato. “Symptoms of Psychosis in Schizophrenia, Schizoaffective Disorder, and Bipolar Disorder: A Comparison of African Americans and Caucasians in the Genomic Psychiatry Cohort.” American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 171, no. 4 (June 2016): 546–55. https://doi.org/10.1002/ajmg.b.32409.
S.M., Strakowski, Keck Jr. P.E., Arnold L.M., Collins J., Wilson R.M., Fleck D.E., Corey K.B., et al. “Ethnicity and Diagnosis in Patients with Affective Disorders.” Journal of Clinical Psychiatry 64, no. 7 (2003): 747. http://psycnet.apa.org/record/2003-05949-003.
Saey, Tina Hesman. “Expert Panel Approves Human Gene Editing.” Science News for Students, 2015. https://www.sciencenewsforstudents.org/article/expert-panel-approves-human-gene-editing.
———. “Gene Editing Creates Buff Beagles.” Science News for Students, 2015. https://www.sciencenewsforstudents.org/article/gene-editing-creates-buff-beagles.
———. “Gene Editing Swats at Mosquitoes.” Science News for Students, 2015. https://www.sciencenewsforstudents.org/article/gene-editing-swats-mosquitoes.
———. “Molecular Scissors Fix Disease-Causing Flaw in Human Embryos.” Science News for Students, 2017. https://www.sciencenewsforstudents.org/article/molecular-scissors-fix-disease-causing-flaw-human-embryos.
———. “Most Americans Think It’s OK to Tweak a Baby’s Genes to Prevent Disease.” Science News, n.d.
———. “New Tools Can Fix Genes One Letter at a Time.” Science News for Students, 2017. https://www.sciencenewsforstudents.org/article/new-tools-can-fix-genes-one-letter-time.
———. “Researchers Say CRISPR Edits to a Human Embryo Worked. But Critics Still Doubt It.” Science News, 2018. https://www.sciencenews.org/article/researchers-confirm-crispr-edits-human-embryo-worked.
———. “Resistance to CRISPR Gene Drives May Arise Easily.” Science News, 2017. https://www.sciencenews.org/article/resistance-crispr-gene-drives-may-arise-easily.
Seed, Kimberley D. “Battling Phages: How Bacteria Defend against Viral Attack.” Edited by Virginia L. Miller. PLOS Pathogens 11, no. 6 (June 11, 2015): e1004847. https://doi.org/10.1371/journal.ppat.1004847.
Shin, Ha Youn, Chaochen Wang, Hye Kyung Lee, Kyung Hyun Yoo, Xianke Zeng, Tyler Kuhns, Chul Min Yang, Teresa Mohr, Chengyu Liu, and Lothar Hennighausen. “CRISPR/Cas9 Targeting Events Cause Complex Deletions and Insertions at 17 Sites in the Mouse Genome.” Nature Communications 8 (2017). https://doi.org/10.1038/ncomms15464 This article promotes the idea that Cas9 can potentially cause inappropriate edits to DNA. However, if used as a two-step process, Cas9 could maintain its accuracy in editing DNA.
Sternberg, Samuel H, Sy Redding, Martin Jinek, Eric C Greene, and Jennifer A Doudna. “DNA Interrogation by the CRISPRRNA-Guided Endonuclease Cas9.” Nature 507, no. 7490 (2014): 1–17. http://dx.doi.org/10.1038/nature13011%0Apapers3://publication/doi/10.1038/nature13011.
Sullivan, P F, K S Kendler, and M C Neale. “Schizophrenia as a Complex Trait - Evidence from a Meta- Analysis of Twin Studies.” Archives of General Psychiatry 60, no. 12 (2003): 1187–92. https://jamanetwork.com/journals/jamapsychiatry/fullarticle/208134.
Thompson, Helen. “Scientists Hide a Real Movie within a Germ’s DNA.” Science News for Students, 2017. https://www.sciencenewsforstudents.org/article/scientists-hide-real-movie-within-germs-dna.
Wanet, A, A Tacheny, … T Arnould - Nucleic acids, and undefined 2012. “MiR-212/132 Expression and Functions: Within and beyond the Neuronal Compartment.” Academic.Oup.Com. Accessed August 12, 2018. https://academic.oup.com/nar/article-abstract/40/11/4742/2409307.
Zhuo, Chuanjun, Weihong Hou, Lirong Hu, Chongguang Lin, Ce Chen, and Xiaodong Lin. “Genomic Editing of Non-Coding RNA Genes with CRISPR/Cas9 Ushers in a Potential Novel Approach to Study and Treat Schizophrenia.” Frontiers in Molecular Neuroscience 10 (February 3, 2017): 28. https://doi.org/10.3389/fnmol.2017.00028 This article describes how the Cas9 nuclease locates DNA for editing.
Zielinski, Sarah. “Even Some Olympic Athletes Cheat with Drugs.” Science News for Students, 2016.

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