How Drugs Work

CONTENTS OF CURRICULUM UNIT 12.05.09

  1. Unit Guide
  1. Introduction
  2. Overview
  3. Rationale
  4. Background
  5. Objectives
  6. Strategies
  7. Classroom Activities
  8. Student Resources
  9. Appendix-Content Standards
  10. Endnotes
  11. Annotated Bibliography

Cardiovascular Medications, Beta-Blockers and their Effect on Cells

Deborah Smithey

Published September 2012

Tools for this Unit:

Overview

The method of introducing cardiovascular medications into the body will vary. Drug delivery to the cardiovascular system is unique because of the anatomy and physiology of the vascular system. The vascular system supplies blood and nutrients to all organs of the body.3 Delivery of drugs to the cardiovascular system is approached on three levels: routes of drug delivery, formulation, and application to various diseases. Formulation for drug delivery into the cardiovascular system range from controlled release preparations to the delivery of proteins and peptides. Biomedical engineering research scientists are developing cell selective target drugs. Nanotechnology is another way of improving the systematic administration of drugs for cardiovascular disorders. Cell-selective targeted drug delivery is another way to maximize the effectiveness of a drug and limit the pharmacological activity to relevant tissues thereby limiting the exposure to other cells.4 Many different categories of drugs are used to treat cardiovascular disease. The unit will concentrate on beta-blockers drugs. The history of beta-blockers and how they affect the cell will be examined in this unit.

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