How Drugs Work

CONTENTS OF CURRICULUM UNIT 12.05.03

  1. Unit Guide
  1. Introduction
  2. Rationale
  3. Objective
  4. Background
  5. Physiology of Blood Pressure
  6. Systemic Vascular Resistance and Flow Etiology
  7. Non-Pharmacologic Treatment for Hypertension
  8. Pharmacological Treatments for Hypertension
  9. Activities
  10. Chronic Activity
  11. Acute Activities
  12. Final Discussion Questions
  13. Implementing District Standards
  14. Endnotes with Annotated Bibliography

The Down-Low (DL) on High Blood Pressure

Stephen Lewia

Published September 2012

Tools for this Unit:

Final Discussion Questions

The following is a list of final discussion questions, broken down by Bloom's Taxonomy, which can be used at the discretion of the teacher. Lower performing students could work on these questions in small groups. Medium performing students could work on these questions individually. Higher performing students could be questioned in a Socratic format.

Remembering:

  • Define hypertension.
  • What is a normal blood pressure?
  • What are some endogenous causes of hypertension?
  • What are some exogenous causes of hypertension?

Understanding:

  • Explain how each pharmaceutical class can decrease high blood pressure?
  • Paraphrase the relationship among vessel radius, flow, and resistance.

Applying:

- If you could create a drug that treats hypertension, which pathway would you use and why?

- Choose a good pharmaceutical agent for the following patients and why:

  • 80 year old male, obese, kidney failure
  • 45 year old female, history of hypertension, stressful job
  • Challenge: 75 year old male, complaining of chest pain

Analyzing:

  • Compare and contrast exogenous and endogenous factors.
  • Compare and contrast diuretics versus beta–blocking medication.

Evaluating:

  • Defend the use of pharmaceutical agents in the reduction of high blood pressure versus natural means.
  • Do you agree or disagree with the use of pharmaceuticals for ANY patient?

Creating:

- Pretend you are the marketing coordinator for a major pharmaceutical company. Create a one–minute pitch on one of the medications studied in this unit. Consider the following:

  • The target audience
  • Type of media used
  • Selling points for your medication

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