How Drugs Work

CONTENTS OF CURRICULUM UNIT 12.05.03

  1. Unit Guide
  1. Introduction
  2. Rationale
  3. Objective
  4. Background
  5. Physiology of Blood Pressure
  6. Systemic Vascular Resistance and Flow Etiology
  7. Non-Pharmacologic Treatment for Hypertension
  8. Pharmacological Treatments for Hypertension
  9. Activities
  10. Chronic Activity
  11. Acute Activities
  12. Final Discussion Questions
  13. Implementing District Standards
  14. Endnotes with Annotated Bibliography

The Down-Low (DL) on High Blood Pressure

Stephen Lewia

Published September 2012

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Endnotes with Annotated Bibliography

  1. Mendez, M. A., R. Cooper, R. Wilks, A. Luke, and T. Forrester. 2003. Income, education, and blood pressure in adults in Jamaica, a middle–income developing country. International Journal of Epidemiology 32 (3) (Jun): 400–8.
  2. Lilly, Leonard S. 1993. Pathophysiology of heart disease: A collaborative project of medical students and faculty. Malvern, Pa., U.S.A.: Lea & Febiger. Krakoff, Lawrence R. 1995. This book is written at a college level; however covers heart disease in its entirety.
  3. Silverthorn, Dee Unglaub. Human Physiology: An Integrated Approach. San Francisco: Pearson/Benjamin Cummings, 2007. College textbook, used for upper level college physiology courses.
  4. Aldridge, Susan. Magic Molecules: How Drugs Work. 2008. Written at an advanced high school level, this book has some great information on drug mechanisms and pathophysiology while still being an enjoyable read.
  5. Kaplan, Norman M., and Joseph Flynn T. Kaplan's Clinical Hypertension. Philadelphia: Lippincott Williams & Wilkins, 2006. This book is written by clinicians for clinicians. Likewise, it contains acronyms and words that can be confusing to those not familiar with medical terminology.
  6. Sanders, Mick J., Kim McKenna, Lawrence M. Lewis, and Gary Quick. 1994. Mosby's paramedic textbook. St. Louis, Mo.: Mosby Lifeline. Written at a college level, this book contains condensed descriptions of pathophysiology and pharmacology while explaining emergency treatment for related disorders.
  7. Lerman, A., E. K. Sandok, F. L. Hildebrand Jr, and J. C. Burnett Jr. 1992. Inhibition of endothelium–derived relaxing factor enhances endothelin–mediated vasoconstriction. Circulation 85 (5) (May): 1894–8. Great paper that discusses EDRF and how it regulates the constriction of arterial endothelia.
  8. Weir, Matthew R. Hypertension. Philadelphia: American College of Physicians, 2005. This book contain an overview of pathophysiology and treatment for high blood pressure. It is written for clinicians, and likewise contains a lot of medical jargon.
  9. Krakoff, Lawrence R. 1995. Management of the hypertensive patient. New York: Churchill Livingstone. I found this resource extremely helpful for all topics related to hypertension. Krakoff made sure to include all facets of a hypertensive patient, including epidemiology and nutrition as well as pharmacology. This book is written at a upper college level.

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