Physiological Determinants of Global Health

CONTENTS OF CURRICULUM UNIT 15.06.09

  1. Unit Guide
  1. Introduction
  2. Rationale
  3. Curriculum Content
  4. Teaching Strategies and Activities
  5. Teacher Resources
  6. Standards
  7. Works Cited
  8. Appendix
  9. Note

The Role of Hormones in Homeostasis

Andrea Lynn Zullo

Published September 2015

Tools for this Unit:

Works Cited

Boron, Walter F., and Emile L. Boulpaep. Medical Physiology: A Cellular and Molecular Approach. Updated ed. Philadelphia, Pa.: Elsevier Saunders, 2005.

"Cushing's Syndrome." NADF. Accessed May 1, 2015. http://www.nadf.us/adrenal-diseases/cushings-syndrome/. A survey of Cushing’s Syndrome.

"Goiter." American Thyroid Association. June 4, 2012. Accessed July 11, 2015. http://www.thyroid.org/what-is-a-goiter/. An explanation of the formation of goiters.

Graham, M. "AAS, Growth Hormone, and Insulin Abuse: Psychological and Neuroendocrine Effects." Ther Clin Risk Manag 4, no. 3 (2008): 587-97. An excellent review of the abuse of hormone therapy.

"Growth Hormone Deficiency - Children: MedlinePlus Medical Encyclopedia." U.S National Library of Medicine. Accessed July 11, 2015. http://www.nlm.nih.gov/medlineplus/ency/article/001176.htm. This resource provides a clear explanation of how GH deficiency affects maturation.

Gupta, V. "Adult Growth Hormone Deficiency." Indian J Endocrinol Metab. 15, no. 3 (2011): S197–S202. Accessed July 10, 2015. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183535/. This article demonstrates some of the effects of GH deficiency in adults.

"Hashimoto's Disease." Treatments and Drugs. Accessed July 11, 2015. http://www.mayoclinic.org/diseases-conditions/hashimotos-disease/basics/treatment/con-20030293. This article outlines the basic treatments and drugs in Hashimoto’s disease.

Hillier, S. "Role of LH in Folliculogenisis during the Menstrual Cycle." J Gynecol Obstet Biol Reprod (Paris) 31, no. 2 (2002). Accessed July 10, 2015. http://www.ncbi.nlm.nih.gov/pubmed/11981484. This review outlines the multifaceted role of LH in ovulation.

Kennedy, M. "Blood Sugar & Other Hormones." Diabetes Education Online. Accessed July 9, 2015. http://dtc.ucsf.edu/types-of-diabetes/type1/understanding-type-1-diabetes/how-the-body-processes-sugar/blood-sugar-other-hormones/. A quick primer on the hormones used in blood glucose regulation.

"Menopausal Hormone Therapy and Cancer Risk." Menopausal Hormone Therapy and Cancer Risk. Accessed July 11, 2015. http://www.cancer.org/cancer/cancercauses/othercarcinogens/medicaltreatments/menopausal-hormone-replacement-therapy-and-cancer-risk. A very informative analysis of the connection between estrogen hormone therapy and cancer.

Milas, K. "Hashimoto's Thyroiditis Overview." EndocrineWeb. March 31, 2015. Accessed July 11, 2015. http://www.endocrineweb.com/conditions/hashimotos-thyroiditis/hashimotos-thyroiditis-overview. A student friendly thyroiditis overview.

Moreau, O. K., et al. "Growth Hormone Replacement Therapy in Patients with Traumatic Brain Injury." Journal of Neurotrauma 30, no. 11 (2013): 998-1006. Accessed July 8, 2015. http://online.liebertpub.com/doi/pdf/10.1089/neu.2012.2705. An interesting use of HRT for therapeutic purposes.

Murphy, K., and S. Bloom. "Gut Hormones And The Regulation Of Energy Homeostasis." Nature 444 (2006): 854-59. Accessed July 6, 2015. http://www.nature.com/nature/journal/v444/n7121/full/nature05484.html. A survey of hormones that are responsible for metabolism.

Paddock, C. "The Skeleton Is Part Of The Endocrine System, New Study." Medical News Today. Accessed July 10, 2015. http://www.medicalnewstoday.com/articles/79522.php. A student-friendly explanation of the role of the skeleton in regulating homeostasis.

Randall, M. "The Physiology of Stress: Cortisol and the Hypothalamic-Pituitary-Adrenal Axis." DUJS Online. February 3, 2011. Accessed August 1, 2015. http://dujs.dartmouth.edu/fall-2010/the-physiology-of-stress-cortisol-and-the-hypothalamic-pituitary-adrenal-axis. A great review of corticotropic hormones.

Richter, T. A. "Progesterone Blocks the Estradiol-Stimulated Luteinizing Hormone Surge by Disrupting Activation in Response to a Stimulatory Estradiol Signal in the Ewe." Biology of Reproduction 67, no. 1 (2002): 119-25. Accessed July 10, 2015. http://www.ncbi.nlm.nih.gov/pubmed/12080007. This article explains the wave of hormones released during ovulation.

Sargis, R. "Low Testosterone Treatments." EndocrineWeb. March 17, 2014. Accessed July 9, 2015. http://www.endocrineweb.com/conditions/low-testosterone/low-testosterone-treatments. Treatment options for low testosterone.

------------. "An Overview of the Pineal Gland." EndocrineWeb. June 10, 2014. Accessed July 8, 2015. http://www.endocrineweb.com/endocrinology/overview-pineal-gland. This is an excellent source to introduce students to the function of the pituitary gland.

------------. "What Is Low Testosterone?" EndocrineWeb. January 29, 2015. Accessed July 8, 2015. http://www.endocrineweb.com/conditions/low-testosterone/what-low-testosterone. A quick but thorough explanation of low testosterone.

Strowski, M. Z. "Somatostatin Inhibits Insulin and Glucagon Secretion via Two Receptor Subtypes: An in Vitro Study of Pancreatic Islets from Somatostatin Receptor 2 Knockout Mice." Endocrinology 141, no. 1 (2000): 111-17. Accessed July 10, 2015. http://www.ncbi.nlm.nih.gov/pubmed/10614629. This article demonstrates the role of somatostatin in the suppression of glucose regulation.

"The Official Site of Andre the Giant: Biography." The Official Site of Andre the Giant: Biography. Accessed July 11, 2015. http://www.andrethegiant.com/about/bio.html. I recommend this website for students to show the results of GH overexpression.

"Thyroid-Stimulating Hormone (TSH)." WebMD. November 14, 2014. Accessed July 8, 2015. http://www.webmd.com/women/thyroid-stimulating-hormone-tsh. This article is a review of TSH structure and function.

Turillazzi, E., et al. "Side Effects of AAS Abuse: An Overview." MRMC Mini-Reviews in Medicinal Chemistry 11, no. 5 (2011): 374-89. Accessed July 12, 2015. http://www.ncbi.nlm.nih.gov/pubmed/21443513. An excellent review of anabolic steroid abuse side effects.

Vellanki, P. "Polycystic Ovary Syndrome in Female Teenagers and Women." EndocrineWeb. October 29, 2014. Accessed July 10, 2015. http://www.endocrineweb.com/conditions/reproduction/polycystic-ovary-syndrome-pcos-female-teenagers-women. PCOS symptoms and development.

Walker, K. "Low Testosterone Diagnosis." EndocrineWeb. October 7, 2011. Accessed July 8, 2015. http://www.endocrineweb.com/conditions/low-testosterone/low-testosterone-diagnosis. An outline of diagnostic procedures for low testosterone.

Wisse, B. "Diabetes Insipidus." U.S National Library of Medicine. November 7, 2013. Accessed July 9, 2015. http://www.nlm.nih.gov/medlineplus/ency/article/000377.htm. An excellent resource that clearly explains the formation of diabetes insipidus.

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